Upcoming Exchange 2013 CU16 requires .NET 4.6.2, .NET 4.6.1 no longer supported

The upcoming CU16 for Exchange 2013 requires .NET 4.6.2.
Expect the CU16 to check for the latest .Net version prior to installing as a prerequisite check.

Microsoft .NET Framework

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The following table identifies the version of the Microsoft .NET Framework that can be used together with each version of Exchange. Supported versions are identified by an X character.

Important:

Releases of .NET Framework that aren't listed in the table below are not supported on any version or release of Exchange. This includes minor and patch-level releases of .NET Framework.

.NET Framework	Exchange 2016 CU3 and later	Exchange 2016 CU2	Exchange 2013 CU15 and later	Exchange 2013 CU14	Exchange 2010 SP3
.NET Framework 3.5					X1
.NET Framework 3.5 SP1					X
.NET Framework 4.0					X1,2
.NET Framework 4.5				X	X1,2
.NET Framework 4.5.1			X	X
.NET Framework 4.5.2	X5	X5	X5	X5
.NET Framework 4.6.1	X5	X3,4,5	X3,4,5	X3,4,5
.NET Framework 4.6.2	X		X	4

1. If you are using Windows Server 2012, the .NET Framework 3.5 must be installed before you can use Exchange 2010 SP3.
2. Exchange 2010 uses only the .NET .NET Framework 3.5 and .NET .NET Framework 3.5 SP1 libraries. It doesn't use the .NET .NET Framework 4.5 libraries if they're installed on the computer. We support the installation of any major or minor version of .NET .NET Framework 4.5 (for example, .NET .NET Framework 4.5.1, .NET .NET Framework 4.5.2, and so on) as long as .NET .NET Framework 3.5 or .NET .NET Framework 3.5 SP1 are also installed on the computer.
3. If you're upgrading from a previously installed Exchange cumulative update, we strongly recommend that you install the latest cumulative update before .NET Framework 4.6.1 and its related post-release fixes.
4. .NET Framework 4.6.1 requires post-release fixes if you want to install it on a server running a supported version of Exchange. The following are the .NET Framework 4.6.1 post-release fixes needed for Exchange.

• Windows Server 2012 R2 Hotfix rollup for the .NET Framework 4.6 and 4.6.1 in Windows (KB3146715) 64 bit
• Windows Server 2012 Hotfix rollup for the .NET Framework 4.6 and 4.6.1 in Windows (KB3146714) 64 bit
• Windows Server 2008 R2 (Exchange 2013 CU13 and later only) Hotfix rollup for the .NET Framework 4.6 and 4.6.1 in Windows (KB3146716) 64 bit
  
  
  5. Starting with Exchange 2016 CU5 and Exchange 2013 CU16, .NET Framework 4.6.1 and         4.5.2 will no longer be supported with Exchange 2016 or Exchange 2013. While those               versions of .NET Framework are supported by Exchange 2016 CU4, we strongly                       recommend that you upgrade servers running Exchange 2016 to .NET Framework 4.6.2.

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