Expect the CU16 to check for the latest .Net version prior to installing as a prerequisite check.
Microsoft .NET Framework
The following table identifies the version of the Microsoft .NET
Framework that can be used together with each version of Exchange. Supported
versions are identified by an X character.
 Important: |
Releases of .NET Framework that aren't listed in the table below are not
supported on any version or release of Exchange. This
includes minor and patch-level releases of .NET Framework.
|
.NET Framework
|
Exchange 2016 CU3 and later
|
Exchange 2016 CU2
|
Exchange 2013 CU15 and later
|
Exchange 2013 CU14
|
Exchange 2010 SP3
|
.NET
Framework 3.5
|
X1
|
||||
.NET
Framework 3.5 SP1
|
X
|
||||
.NET
Framework 4.0
|
X1,2
|
||||
.NET
Framework 4.5
|
X
|
X1,2
|
|||
.NET
Framework 4.5.1
|
X
|
X
|
|||
.NET
Framework 4.5.2
|
X5
|
X5
|
X5
|
X5
|
|
.NET
Framework 4.6.1
|
X5
|
X3,4,5
|
X3,4,5
|
X3,4,5
|
|
.NET
Framework 4.6.2
|
X
|
X
|
4
|
- If you are using Windows Server 2012, the .NET Framework 3.5 must be installed before you can use Exchange 2010 SP3.
- Exchange 2010 uses only the .NET .NET Framework 3.5 and .NET .NET Framework 3.5 SP1 libraries. It doesn't use the .NET .NET Framework 4.5 libraries if they're installed on the computer. We support the installation of any major or minor version of .NET .NET Framework 4.5 (for example, .NET .NET Framework 4.5.1, .NET .NET Framework 4.5.2, and so on) as long as .NET .NET Framework 3.5 or .NET .NET Framework 3.5 SP1 are also installed on the computer.
- If you're upgrading from a previously installed Exchange cumulative update, we strongly recommend that you install the latest cumulative update before .NET Framework 4.6.1 and its related post-release fixes.
- .NET Framework 4.6.1 requires post-release fixes if you want to install it on a server running a supported version of Exchange. The following are the .NET Framework 4.6.1 post-release fixes needed for Exchange.
- Windows Server 2012 R2 Hotfix rollup for the .NET Framework 4.6 and 4.6.1 in Windows (KB3146715) 64 bit
- Windows Server 2012 Hotfix rollup for the .NET Framework 4.6 and 4.6.1 in Windows (KB3146714) 64 bit
- Windows Server 2008 R2 (Exchange 2013 CU13 and later only) Hotfix rollup for the .NET Framework 4.6 and 4.6.1 in Windows (KB3146716) 64 bit
5. Starting with Exchange 2016 CU5 and Exchange 2013 CU16, .NET Framework 4.6.1 and 4.5.2 will no longer be supported with Exchange 2016 or Exchange 2013. While those versions of .NET Framework are supported by Exchange 2016 CU4, we strongly recommend that you upgrade servers running Exchange 2016 to .NET Framework 4.6.2.
Is there any recommended Update procedure to Go from ex13 cu14 to cu16?
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